• Jiajun Luo

    Instructor @ Institute for Population and Precision Health, the University of Chicago

     

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    Welcome!

    Hi! I am a Pathway to Independence Instructor at the Institute for Population and Precision Health (IPPH), the University of Chicago. I received my Ph.D. degree in Environmental Health Sciences from Yale School of Public Health. My research primarily focuses on three areas: (1) Environmental epidemiology; (2) Social context; (3) Application of causal inference in epidemiology.

  • Education 

    Yale School of Public Health

    Ph.D. (2018-2021)

    Department of Environmental Health Sciences

    Yale School of Public Health

    Master of Public Health (2015-2017)

    Department of Environmental Health Sciences

    Tsinghua University

    Bachelor of Science (2011-2015)

    Department of Building Sciences

  • Research

    I was primarily trained in environmental epidemiology. My research interest lies in how the broad environment, including social context and physical environment, shapes individuals’ health. My current research mainly covers two fields: 1) how endocrine disrupting chemicals (EDCs) affect child’s brain- and neuro-development; and 2) how social determinants of health (SDOH) interact with environmental pollutants contributing to the widening health disparities among disadvantaged populations.

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    Poly- and per-fluoroalkyl substances (PFAS)

    PFAS are a large, complex, and ever-expanding group of manufactured chemicals that are widely used to make various types of everyday products. For example, they keep food from sticking to cookware, make clothes and carpets resistant to stains, and create firefighting foam that is more effective. Animal studies and population-based studies have suggested that prenatal exposure to PFAS may induce neurodevelopmental disorders during childhood. My research aims to investigate the impact of prenatal PFAS exposure on the child's neurodevelopment using cohorts from Denmark and China.

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    Social context

    Social contextual deprivation encompasses the collective challenges faced by a community or population, including but not limited to poverty levels, quality of housing, access to healthcare, and employment opportunities. At the University of Chicago, I take advantage of the Chicago Multiethnic Prevention and Surveillance Study (COMPASS) to investigate how these social disadvantages contribute to health disparities. Several highlights from my work in this area: 1) I constructed a new metric for spatial accessibility of primary care in Chicago and linked this metric with hypertension; 2) I used a new method to estimate the joint effect of multiple correlated social contextual factors and identified community poverty as the primary contributor to adverse health outcome; and 3) I recently used g-estimation to assess the influence of unmeasured confounding regarding how discrimination affects mental health.

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    Causal Inference in Environmental Epidemiology

    Environmental epidemiology poses new challenges to epidemiologic methodologies. For example, mixture exposure and lagging exposure are common in environmental epidemiology, but epidemiologists are still debating what approaches we can use to address these issues. One of my research goals is to develop applied analytical approachs within the causal inference framework that can help solve problems in environmental epidemiology.

  • Publications

    Published Journal Articles

    • Luo, J., Kibriya, M. G.,Jasmine, F., Shaikh, A., Jin, Z., Sargis, R., ... & Aschebrook-Kilfoy, B. (2023). Duration sensitive association between air pollution exposure and changes in cardiometabolic biomarkers: Evidence from a predominantly African American cohort. Environmental Research, 117496
    • Luo, J., Krakowka, W. I., Craver, A., Connellan, E., King, J., Kibriya, M. G., ... & Aschebrook-Kilfoy, B. (2023). The Role of Health Insurance Type and Clinic Visit on Hypertension Status Among Multiethnic Chicago Residents. American Journal of Health Promotion, 08901171231209674.
    • Luo, J., Powell, J., Ross, S., Johnson, J., Olopade, C. O., Pinto, J., ... & Aschebrook-Kilfoy, B. (2023). Evaluating the impact of sickle cell disease on COVID-19 susceptibility and severity: a retrospective cohort study based on electronic health record. Frontiers in Epidemiology, 3, 1241645
    • Luo,J., Kibriya, M. G.,Chen, H., Kim, K., Ahsan, H., Olopade, O. I., ... & Huo, D. (2023). A metabolome-wide case-control study of african american breast cancer patients. BMC cancer, 23(1), 1-11.
    • Luo, J., Kibriya, M. G., Shah, S., Craver, A., Cruz, S., King, J., ... & Aschebrook-Kilfoy, B. (2023). The impact of neighborhood disadvantage on asthma prevalence in a predominantly African American Chicago-based cohort. American Journal of Epidemiology, DOI: https://doi.org/10.1093/aje/kwad015 
    • Wang, Z., Luo, J. (co-first author),Zhang, Y., Li, J., Zhang, J., Tian, Y., & Gao, Y. (2023). High maternal glucose exacerbates the association between prenatal per-and polyfluoroalkyl substance exposure and reduced birth weight. Science of The TotalEnvironment, 858, 160130
    • Luo, J., Aschebrook-Kilfoy, B., & Olopade, C. O. (2022). Maps of solid-fuel use and household air pollution. The Lancet Global Health, 10(10), e1361-e1362.
    • Luo, J., Kibriya, M. G., Zakin, P., Craver, A., Connellan, L., Tasmin, S., ... & Aschebrook-Kilfoy, B. (2022). Urban spatial accessibility of primary care and hypertension control and awareness on Chicago’s South Side: A Study from the COMPASS Cohort. Circulation: Cardiovascular Quality and Outcomes, 15(9), e008845
    • Luo, J., Craver, A., Bahl, K., Stepniak, L., Moore, K., King, J., ... & Aschebrook-Kilfoy, B. (2022). Etiology of non-Hodgkin lymphoma: a review from epidemiologic studies. Journal of the National Cancer Center, DOI: https://doi.org/10.1016/j.jncc.2022.08.003
    • Luo, J., Craver, A., Zakin, P., Stepniak, L., Moore, K., King, J., ... & Aschebrook‐Kilfoy, B. (2022). Race may modify the association between blood type and COVID‐19 infection. EJHaem, 3(3), 903-907. DOI: https://doi.org/10.1002/jha2.539
    • Gao, Y., Luo, J. (co-first author), Zhang, Y., Pan, C., Ren, Y., Zhang, J., ... & Shanghai Birth Cohort. (2022). Prenatal exposure to per-and polyfluoroalkyl substances and child growth trajectories in the first two years. Environmental Health Perspectives, 130(3), 037006.
    • Luo, J., Ramlau-Hansen, C. H., Kesmodel, U.S., Xiao, J., Vasiliou, V., Deziel, N.C., … & Liew, Z. (2022). Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort. Environmental Health Perspectives, 128(0), 017006
    • Luo, J., Xiao, J., Gao, Y., Ramlau-Hansen, C. H., Toft, G., Li, J., ... & Liew, Z. (2020). Prenatal exposure to perfluoroalkyl substances and behavioral difficulties in childhood at 7 and 11 years. Environmental Research. DOI: https://doi.org/10.1016/j.envres.2020.110111.
    • Luo, J., Wu, W., Zhang, P., Chen, X., Feng, Y., Ma, N., ... & Guo, P. (2020). Zinc levels and birth weight in pregnant women with gestational diabetes mellitus: a matched cohort study in China. The Journal of Clinical Endocrinology & Metabolism, 105(7), dgaa171.
    • Luo, J., Li, H., Deziel, N. C., Huang, H., Zhao, N., Ma, S., ... & Zhang, Y. (2020). Genetic susceptibility may modify the association between cell phone use and thyroid cancer: A population-based case-control study in Connecticut. Environmental Research, 182, 109013.
    • Luo, J., Deziel, N. C., Huang, H., Chen, Y., Ni, X., Ma, S., ... & Zhang, Y. (2019). Cell phone use and risk of thyroid cancer: a population-based case–control study in Connecticut. Annals of epidemiology, 29, 39-45.
    • Luo, J., Liu, Z., Pei, K. Y., Khan, S. A., Wang, X., Yang, M., ... & Zhang, Y. (2019). The Role of Bowel Preparation in Open, Minimally Invasive, and Converted-to-Open Colectomy. Journal of Surgical Research, 242, 183-192.
    • Liu, Z., Luo, J. J., Pei, K. Y., Khan, S. A., Wang, X. X., Zhao, Z. X., ... & Zhang, Y. (2020). Joint effect of pre-operative anemia and perioperative blood transfusion on outcomes of colon-cancer patients undergoing colectomy. Gastroenterology report, 8(2), 151-157.
    • Gao, Y., Yu, Y., Xiao, J., Luo, J., Zhang, Y., Tian, Y., ... & Liew, Z. (2020). Association of Grandparental and Parental Age at Childbirth With Autism Spectrum Disorder in Children. JAMA network open, 3(4), e202868-e202868.
    • Liew, Z., Luo, J., Nohr, E. A., Bech, B. H., Bossi, R., Arah, O. A., & Olsen, J. (2020). Maternal Plasma Perfluoroalkyl Substances and Miscarriage: A Nested Case–Control Study in the Danish National Birth Cohort. Environmental health perspectives, 128(4), 047007.
    • Maassel, N. L., Fleming, M. M., Luo, J., Zhang, Y., & Pei, K. Y. (2020). Model for End-Stage Liver Disease Sodium as a Predictor of Surgical Risk in Cirrhotic Patients With Ascites. Journal of Surgical Research, 250, 45-52.
    • Tsay, C., Luo, J., Zhang, Y., Attaran, R., Dardik, A., & Chaar, C. I. O. (2019). Perioperative outcomes of lower extremity revascularization for rest pain and tissue loss Tsay-Perioperative outcomes for rest pain v tissue loss. Annals of vascular surgery.
    • Jorshery, S. D., Luo, J., Zhang, Y., Sarac, T., & Chaar, C. I. O. (2019). Hybrid surgery for bilateral lower extremity inflow revascularization. Journal of vascular surgery, 70(3), 768-775.
    • Heller, D. R., Jean, R. A., Luo, J., Kurbatov, V., Grisotti, G., Jacobs, D., ... & Khan, S. A. (2019). Practice patterns and guideline non-adherence in surgical management of appendiceal carcinoid tumors. Journal of the American College of Surgeons, 228(6), 839-851.
    • Fleming, M. M., Liu, F., Luo, J., Zhang, Y., & Pei, K. Y. (2019). Predictors of 30 day readmission following percutaneous cholecystostomy. Journal of Surgical Research, 233, 1-7.
    • Fleming, M. M., DeWane, M. P., Luo, J., Liu, F., Zhang, Y., & Pei, K. Y. (2019). A propensity score matched comparison of readmissions and cost of laparoscopic cholecystectomy vs percutaneous cholecystostomy for acute cholecystitis. The American Journal of Surgery, 217(1), 83-89.
    • Fleming, M. M., DeWane, M. P., Luo, J., Zhang, Y., & Pei, K. Y. (2018). Ascites: A marker for increased surgical risk unaccounted for by the model for end-stage liver disease (MELD) score for general surgical procedures. Surgery, 164(2), 233-237.
    • Tang, Z., Zhang, H., Bai, H., Chen, Y., Zhao, N., Zhou, M., Luo, J., ... & Zhang, C. (2018). Residential mobility during pregnancy in Urban Gansu, China. Health & place, 53, 258-263.
    • Jacobs, D., Zhu, R., Luo, J., Grisotti, G., Heller, D. R., Kurbatov, V., ... & Khan, S. A. (2018). Defining early-onset colon and rectal cancers. Frontiers in oncology, 8, 504.
    • Cao, J., Weschler, C. J., Luo, J., & Zhang, Y. (2016). C m-history method, a novel approach to simultaneously measure source and sink parameters important for estimating indoor exposures to phthalates. Environmental science & technology, 50(2), 825-834.

  • Contact me

    Institute for Population and Precision Health
    5841 S. Maryland Avenue
    MC 6100, Room TN-622
    Chicago, IL 60637
    jiajun.luo93@gmail.com; jluo3@uchicago.edu
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